Title
Kontaminacija hrane ftalatima usled njihove migracije iz plastične ambalaže
Creator
Bogdanović, Danica S., 1987-
CONOR:
74508041
Copyright date
2021
Object Links
Select license
Autorstvo-Nekomercijalno-Bez prerade 3.0 Srbija (CC BY-NC-ND 3.0)
License description
Dozvoljavate samo preuzimanje i distribuciju dela, ako/dok se pravilno naznačava ime autora, bez ikakvih promena dela i bez prava komercijalnog korišćenja dela. Ova licenca je najstroža CC licenca. Osnovni opis Licence: http://creativecommons.org/licenses/by-nc-nd/3.0/rs/deed.sr_LATN. Sadržaj ugovora u celini: http://creativecommons.org/licenses/by-nc-nd/3.0/rs/legalcode.sr-Latn
Language
Serbian
Cobiss-ID
Theses Type
Doktorska disertacija
description
Datum odbrane: 30.09.2021.
Other responsibilities
Academic Expertise
Prirodno-matematičke nauke
Academic Title
-
University
Univerzitet u Nišu
Faculty
Prirodno-matematički fakultet
Group
Odsek za hemiju
Alternative title
Phthalates food contamination due to their migration from plastic packaging
: doctoral dissertation
Publisher
[D. S. Bogdanović]
Format
[21],166 listova
description
Biobibliografija: list. 159-165;
Bibliografija: listovi 150-170.
description
environmental chemistry
Abstract (en)
Phthalates are used as plasticizers for plastic materials. Bearing in mind that phthalates easily migrate to the environment and represent environmentaly risk substances, it is important to know their concentration in plastic material and food, as well as the conditions under which phthalates migrate from plastic articles. The following phthalates were tested: dimethyl phthalate, di-n-butyl phthalate, benzylbutyl phthalate, di(2-ethylhexyl) phthalate and di-n-octyl phthalate. Their migration into milk, dairy products, alcoholic beverages (white brandy and synthetic wine) and artificial saliva from plastic articles made of the following polymers: polyvinyl chloride (PVC), polyethylene terephthalate, high density polyethylene, low density polyethylene, polypropylene, polystyrene and polycarbonate was monitored. A liquid-liquid extraction method was developed for three different types of food matrix: high fat food, low fat food and non-fat food, which was confirmed by quantification of phthalates in food samples using GC-MS technique by developed and optimized method for determining phthalate concentration in food samples of different degree of fat: water, alcoholic beverages, milk. The development and optimization of the method for determining the concentration of phthalates in samples of PVC plastic articles using the GC-MS technique and the development of a new method of quantifiTrellocation of phthalates in PVC plastic articles using the FTIR technique were performed. Finally, the degree of migration of phthalates from plastic materials in contact with food and pharmaceutical products and PVC toys into the recipient model was examined. The analysis of factors influencing the migration of phthalates from plastic articles to the appropriate recipient was performed (recipient model, milk and dairy products, artificial saliva): temperature, ultrasound, fat percentage of milk and dairy products, UV-A, UV-C light.
Abstract (en)
This dissertation is a part of the research performed within the Grant of the Ministry of Education, Science and Technological Development of the Republic of Serbia TR 31060 “Production of new dietary dairy products for high-risk population based on qualitative and quantitative analysis of health risk markers for milk consumption” and III 41018 „Preventive, therapeutic, and ethical approach to the preclinical and clinical researches of genes and modulators of redox cell signalling in immune, inflammatory and proliferative cell response” and within the research program – Contract No. 451-03-68/2020-14/200124 and Contract No. 451-03-9/2021-14/200124. The experimental part of this thesis was done in the Laboratory for Mass Spectrometry and the Laboratory for Applied and Industrial Chemistry of the Department of Chemistry of the Faculty of Science in Nis, as well as in the Laboratory for Spectroscopy of the Faculty of Technology in Leskovac, University of Nis.
Authors Key words
Ftalati, kontaminacija, migracija, plastični artikli u kontaktu sa hranom, plastični artikli u kontaktu sa farmaceutskim proizvodima, dečje igračke, hrana, veštačka pljuvačka, GC-MS tehnika, FTIR tehnika
Authors Key words
Phthalates, contamination, migration, food contact materials, pharmaceutical contact materials, children's toys, food, artificial saliva, GC-MS technique, FTIR technique
Classification
641.1:[661.8ʹ078.4+621.798](043.3)
Subject
P 003
Type
Tekst
Abstract (en)
Phthalates are used as plasticizers for plastic materials. Bearing in mind that phthalates easily migrate to the environment and represent environmentaly risk substances, it is important to know their concentration in plastic material and food, as well as the conditions under which phthalates migrate from plastic articles. The following phthalates were tested: dimethyl phthalate, di-n-butyl phthalate, benzylbutyl phthalate, di(2-ethylhexyl) phthalate and di-n-octyl phthalate. Their migration into milk, dairy products, alcoholic beverages (white brandy and synthetic wine) and artificial saliva from plastic articles made of the following polymers: polyvinyl chloride (PVC), polyethylene terephthalate, high density polyethylene, low density polyethylene, polypropylene, polystyrene and polycarbonate was monitored. A liquid-liquid extraction method was developed for three different types of food matrix: high fat food, low fat food and non-fat food, which was confirmed by quantification of phthalates in food samples using GC-MS technique by developed and optimized method for determining phthalate concentration in food samples of different degree of fat: water, alcoholic beverages, milk. The development and optimization of the method for determining the concentration of phthalates in samples of PVC plastic articles using the GC-MS technique and the development of a new method of quantifiTrellocation of phthalates in PVC plastic articles using the FTIR technique were performed. Finally, the degree of migration of phthalates from plastic materials in contact with food and pharmaceutical products and PVC toys into the recipient model was examined. The analysis of factors influencing the migration of phthalates from plastic articles to the appropriate recipient was performed (recipient model, milk and dairy products, artificial saliva): temperature, ultrasound, fat percentage of milk and dairy products, UV-A, UV-C light.
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