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Bošković, Mirjana V. 1976-
Praćenje biohemijskih parametara zapaljenja, oksidativnog stresa i apoptoze u pljuvačci pacijenata sa fiksnim i mobilnim stomatološkim protetskim nadoknadama
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Academic metadata
Doktorska disertacija
Medicinske nauke
Univerzitet u Nišu
Medicinski fakultet
Katedra za bolesti zuba, oralnu medicinu i parodontologiju
Other Theses Metadata
Monitoring of biochemical parameters of inflammation, oxidative stress and apoptosis in the saliva of patients with fixed and mobile dental prosthetic restorations
[M. Bošković]
[6], 82 lista
Biografija autora: list 82
Datum odbrane: 17.02.2017.
Prosthetic dentistry
Sokolović, Dušan (mentor)
Kesić, Ljiljana (član komisije)
Puškar, Tatjana (član komisije)
Tooth loss is a huge problem of the modern man. Use of new technologies and dental materials in the fabrication of fixed or mobile dental prosthetic appliances has an impact on the change of some of the biochemical parameters in the patient saliva. It is thought that to a degree, particular materials have an impact on the change of quality and quantity of saliva after their placement in the mouth cavity. The presence of metal ions as free ions in the mouth has got a large potential for the creation of factors that cause oxidative stress. A specially adverse effect has been observed with alloys used in the fabrication of fixed dental prosthetic appliances, since they cause allergic and hypersensitivity reactions in the mouth cavity. It has been shown that use of dental prosthetic appliances induces changes in the morphology and reduced motility of the cells, significant increase of oxidative stress, appearance of cytokines, and cell intoxication. With the placement of fixed dental prosthetic appliances patients tend to adapt to them much quicker than with mobile appliances, when the clinical signs of inflammation are much more common. With the application of fixed dental prosthetic appliances oxidative stress in the saliva is much less intense than with mobile appliances. A similar relationship has been found in the analysis of parameters of inflammation and markers of apoptosis in the saliva. Increased parameters of inflammation, oxidative stress, and apoptosis in the saliva of patients as the result of fixed dental prosthetic appliances, tend to normalize much more rapidly than with mobile appliances. The analyzed biochemical parameters normalize 30 days after the placement of fixed or mobile dental prosthetic appliances.
saliva, mobile dental prosthetic appliance, fixed dental prosthetic appliance, biochemical parametars of inflammation
612.313:577.1):616.314-76/77(043.3)
B 730
Serbian
533897110
Elektronska teza
Tooth loss is a huge problem of the modern man. Use of new technologies and dental materials in the fabrication of fixed or mobile dental prosthetic appliances has an impact on the change of some of the biochemical parameters in the patient saliva. It is thought that to a degree, particular materials have an impact on the change of quality and quantity of saliva after their placement in the mouth cavity. The presence of metal ions as free ions in the mouth has got a large potential for the creation of factors that cause oxidative stress. A specially adverse effect has been observed with alloys used in the fabrication of fixed dental prosthetic appliances, since they cause allergic and hypersensitivity reactions in the mouth cavity. It has been shown that use of dental prosthetic appliances induces changes in the morphology and reduced motility of the cells, significant increase of oxidative stress, appearance of cytokines, and cell intoxication. With the placement of fixed dental prosthetic appliances patients tend to adapt to them much quicker than with mobile appliances, when the clinical signs of inflammation are much more common. With the application of fixed dental prosthetic appliances oxidative stress in the saliva is much less intense than with mobile appliances. A similar relationship has been found in the analysis of parameters of inflammation and markers of apoptosis in the saliva. Increased parameters of inflammation, oxidative stress, and apoptosis in the saliva of patients as the result of fixed dental prosthetic appliances, tend to normalize much more rapidly than with mobile appliances. The analyzed biochemical parameters normalize 30 days after the placement of fixed or mobile dental prosthetic appliances.
https://phaidrani.ni.ac.rs/detail_object/o:1378?tab=0#mda
