Title
Praćenje biohemijskih parametara zapaljenja, oksidativnog stresa i apoptoze u pljuvačci pacijenata sa fiksnim i mobilnim stomatološkim protetskim nadoknadama
Creator
Bošković, Mirjana V. 1976-
Copyright date
2016
Object Links
Select license
Autorstvo-Nekomercijalno-Bez prerade 3.0 Srbija (CC BY-NC-ND 3.0)
License description
Dozvoljavate samo preuzimanje i distribuciju dela, ako/dok se pravilno naznačava ime autora, bez ikakvih promena dela i bez prava komercijalnog korišćenja dela. Ova licenca je najstroža CC licenca. Osnovni opis Licence: http://creativecommons.org/licenses/by-nc-nd/3.0/rs/deed.sr_LATN. Sadržaj ugovora u celini: http://creativecommons.org/licenses/by-nc-nd/3.0/rs/legalcode.sr-Latn
Language
Serbian
Cobiss-ID
Theses Type
Doktorska disertacija
description
Datum odbrane: 17.02.2017.
Other responsibilities
mentor
Sokolović, Dušan
član komisije
Kesić, Ljiljana
član komisije
Puškar, Tatjana
Academic Expertise
Medicinske nauke
University
Univerzitet u Nišu
Faculty
Medicinski fakultet
Group
Katedra za bolesti zuba, oralnu medicinu i parodontologiju
Alternative title
Monitoring of biochemical parameters of inflammation, oxidative stress and apoptosis in the saliva of patients with fixed and mobile dental prosthetic restorations
Publisher
[M. Bošković]
Format
[6], 82 lista
description
Biografija autora: list 82
description
Prosthetic dentistry
Abstract (en)
Tooth loss is a huge problem of the modern man. Use of new technologies and dental materials in the fabrication of fixed or mobile dental prosthetic appliances has an impact on the change of some of the biochemical parameters in the patient saliva. It is thought that to a degree, particular materials have an impact on the change of quality and quantity of saliva after their placement in the mouth cavity. The presence of metal ions as free ions in the mouth has got a large potential for the creation of factors that cause oxidative stress. A specially adverse effect has been observed with alloys used in the fabrication of fixed dental prosthetic appliances, since they cause allergic and hypersensitivity reactions in the mouth cavity. It has been shown that use of dental prosthetic appliances induces changes in the morphology and reduced motility of the cells, significant increase of oxidative stress, appearance of cytokines, and cell intoxication. With the placement of fixed dental prosthetic appliances patients tend to adapt to them much quicker than with mobile appliances, when the clinical signs of inflammation are much more common. With the application of fixed dental prosthetic appliances oxidative stress in the saliva is much less intense than with mobile appliances. A similar relationship has been found in the analysis of parameters of inflammation and markers of apoptosis in the saliva. Increased parameters of inflammation, oxidative stress, and apoptosis in the saliva of patients as the result of fixed dental prosthetic appliances, tend to normalize much more rapidly than with mobile appliances. The analyzed biochemical parameters normalize 30 days after the placement of fixed or mobile dental prosthetic appliances.
Authors Key words
pljuvaĉka, mobilna stomatološka protetska nadoknada, fiskna stomatološka protetska nadoknada, biohemijski parametri zapaljenja
Authors Key words
saliva, mobile dental prosthetic appliance, fixed dental prosthetic appliance, biochemical parametars of inflammation
Classification
612.313:577.1):616.314-76/77(043.3)
Subject
B 730
Type
Elektronska teza
Abstract (en)
Tooth loss is a huge problem of the modern man. Use of new technologies and dental materials in the fabrication of fixed or mobile dental prosthetic appliances has an impact on the change of some of the biochemical parameters in the patient saliva. It is thought that to a degree, particular materials have an impact on the change of quality and quantity of saliva after their placement in the mouth cavity. The presence of metal ions as free ions in the mouth has got a large potential for the creation of factors that cause oxidative stress. A specially adverse effect has been observed with alloys used in the fabrication of fixed dental prosthetic appliances, since they cause allergic and hypersensitivity reactions in the mouth cavity. It has been shown that use of dental prosthetic appliances induces changes in the morphology and reduced motility of the cells, significant increase of oxidative stress, appearance of cytokines, and cell intoxication. With the placement of fixed dental prosthetic appliances patients tend to adapt to them much quicker than with mobile appliances, when the clinical signs of inflammation are much more common. With the application of fixed dental prosthetic appliances oxidative stress in the saliva is much less intense than with mobile appliances. A similar relationship has been found in the analysis of parameters of inflammation and markers of apoptosis in the saliva. Increased parameters of inflammation, oxidative stress, and apoptosis in the saliva of patients as the result of fixed dental prosthetic appliances, tend to normalize much more rapidly than with mobile appliances. The analyzed biochemical parameters normalize 30 days after the placement of fixed or mobile dental prosthetic appliances.
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