Title
Efekat perkutane koronarne intervencije na prognozu sa akutnim infarktom miokarda bez ST elevacije
Creator
Lazarević, Gordana D. 1976-
Copyright date
2016
Object Links
Select license
Autorstvo-Nekomercijalno-Bez prerade 3.0 Srbija (CC BY-NC-ND 3.0)
License description
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Language
Serbian
Cobiss-ID
Theses Type
Doktorska disertacija
description
Datum odbrane: 07.07.2016.
Other responsibilities
mentor
Perišić, Zoran
Academic Expertise
Medicinske nauke
University
Univerzitet u Nišu
Faculty
Medicinski fakultet
Group
Katedra za hirurgiju
Alternative title
An effect of percutaneous coronary intervention on outcomes in patients with non ST segment elevation myocardial infarction
Publisher
[G. D. Lazarević]
Format
120 listova
description
Biografija: list 176
description
Cardiology
Abstract (en)
Introduction: Data suggest that the prevalence of non ST segment elevation acute coronary syndromes (NSTE-ACS) is higher than that of ST segment elevation myocardial infarction (MI) (STEMI), intrahospital mortality is higher in STEMI, but higher in NSTE-ACS compared to STEMI after 4 years. The aim of the present study is to investigate the effects of percutaneous coronary intervention (PCI) on outcomes in patients with non ST segment elevation MI (NSTEMI).
Patients and methods: The present study included 185 patients who survived MI (A group, patients with NSTEMI, treated with PCI and drugs, B group, patients with STEMI, treated with PCI and drugs and C group, patients with NSTEMI, treated with drugs only). An effect of PCI, as well as the predictive value of markers of necrosis, inflammation, renal function, heart failure on intrahospital and posthospital outcomes were investigated.
Results: Intrahospital complications appeared more frequently in B group, while posthospital complications, including angina pectoris, hemodynamic instability and MACE (death, reinfarction and coronary artery bypass grafting) appeared more frequently in C group. The strongest predictors of death were the C group, female sex, patients who already suffered from MI, heart rate on admission, glycated hemoglobin, urea and creatinine.
Conclusions: The strongest predictors of death were age and heart rate on admission. The average time of survival was significantly shorter in C group, compared to both A and B groups. However, it was not significantly different between A and B groups.
Authors Key words
infarkt miokarda, perkutana koronarna intervencija, markeri nekroze, markeri inflamacije, markeri bubrežne funkcije, markeri srčane insuficijencije, komplikacije
Authors Key words
myocardial infarction, percutaneous coronary intervention, markers of necrosis, inflammation, renal function, heart failure, outcomes, MACE
Classification
616.127-005.8-089.819.5-06-036:577.1(043.3)
Subject
B 530
Type
Elektronska teza
Abstract (en)
Introduction: Data suggest that the prevalence of non ST segment elevation acute coronary syndromes (NSTE-ACS) is higher than that of ST segment elevation myocardial infarction (MI) (STEMI), intrahospital mortality is higher in STEMI, but higher in NSTE-ACS compared to STEMI after 4 years. The aim of the present study is to investigate the effects of percutaneous coronary intervention (PCI) on outcomes in patients with non ST segment elevation MI (NSTEMI).
Patients and methods: The present study included 185 patients who survived MI (A group, patients with NSTEMI, treated with PCI and drugs, B group, patients with STEMI, treated with PCI and drugs and C group, patients with NSTEMI, treated with drugs only). An effect of PCI, as well as the predictive value of markers of necrosis, inflammation, renal function, heart failure on intrahospital and posthospital outcomes were investigated.
Results: Intrahospital complications appeared more frequently in B group, while posthospital complications, including angina pectoris, hemodynamic instability and MACE (death, reinfarction and coronary artery bypass grafting) appeared more frequently in C group. The strongest predictors of death were the C group, female sex, patients who already suffered from MI, heart rate on admission, glycated hemoglobin, urea and creatinine.
Conclusions: The strongest predictors of death were age and heart rate on admission. The average time of survival was significantly shorter in C group, compared to both A and B groups. However, it was not significantly different between A and B groups.
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